The Pittsburgh Steelers defeated the Cleveland Browns in the opening of three "Monday Night Football" twin bills, while the New Orleans Saints defeated the Carolina Panthers to move to 2-0 on the season. Star running back Nick Chubb was helped off the field after suffering a catastrophic leg injury.

players other than Chubb also suffered injuries. Minka Fitzpatrick, a safety for the Steelers, who was hurt in the same collision as Chubb, was forced to leave the contest. Shaq Thompson, a veteran linebacker for the Panthers, was also thought to have sustained a serious injury. Because of a hamstring injury, Saints running back Jamaal Williams missed the team's victory.